Summary Incontinentia pigmenti in horses is a real, genetically characterized condition caused by a specific variant in IKBKG (c.184C>T, p.Arg62*), confirmed in American Quarter Horses and catalogued as OMIA:001899-9796. It produces brindle-like striping that is visually indistinguishable from the BR1 coat variant or from chimerism and somatic mosaicism, but accompanies systemic pathology that the other…

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